Indastering ea lik'hemik'hale, lihlahisoa tsa ho sefa li sebelisoa ho sefa tlhahiso ea lisebelisoa tse tala tsa lik'hemik'hale, li-intermediate le lihlahisoa, joalo ka lisebelisoa tse tala tsa organic reaction, lithethefatsi tsa lik'hemik'hale, li-intermediate tse hloekisitsoeng tsa meriana, likaroloana tsa li-reactants le li-catalysts, tlhoekiso ea li-solvents, le ho tlosoa hoa li-catalyst tse sebedisoang ketsong e itseng ya dikhemikhale.